Intermediate Biostatistics
Biostatistics and Epidemiology
UMass Amherst



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1. Review of BIOSTATS 540
2. Discrete Distributions

3. Introduction to Nonparametrics

4. Categorical Data Analysis

5. Normal Theory Regression
6. Analysis of Variance

7. Logistic Regression
8. Introduction to Survival Analysis
9. (Time permitting) Introduction to Mixed Models


" Technical skills, like fire, can be an admirable servant
and a dangerous master."
- A. Bradford Hill (1971)

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Next Offered
Spring 2022

Welcome to BIOSTATS 640, Intermediate Biostatistics!
Spring 2021
Instructor: Carol Bigelow

Introduction. BIOSTATS 640 is the second of a two-semester sequence of introductory biostatistics.  Similar to BIOSTATS 540, the overall goal is statistical literacy and skills in selected, basic, analyses of biological and health data.  Topics include:  review of introductory biostatistics, selected discrete distributions, introduction to nonparametric tests, analysis of epidemiological tables, single and multiple predictor normal theory regression, logistic regression and introduction to survival analysis.  

Software.  We will be using R in illustrations of data analysis.   However, no prior experience with R is required and you will not be required to use R on any examination.  If you are already a SAS or Stata (or other software) user, you are welcome to use that instead. 

This website is designed for use by
Students enrolled in BIOSTATS 640 Spring 2021
Visitors interested in topic specific resources (lectures, computer illustrations, reference url links)



University of Massachusetts at Amherst
Copyright 2021 University of Massachusetts, Amherst.
This is the course web site for BIOSTATS 640, BiostatisticsProgram, Department of Biostatistics and Epidemiology.
Produced and maintained by the School of Public Health and Health Sciences.
Send comments or questions about this web site to cbigelow@schoolph.umass.edu.
Page updated: April 26, 2021