Ross Lab Publications


  1. 1.A. Gable, M. Qiu, J. Titus, S. Balchand, N.P. Ferenz, N. Ma, E.S. Collins, C. Fagerstrom, J.L. Ross, G. Yang, P. Wadsworth, “Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2,” Molecular Biology of the Cell, 23, 1254-1266 (2012). web Gable-MBOC-2012.pdf doi: 10.1091/mbc.E11-09-0820

  2. 2.D.J. Sharp and J.L. Ross, “Microtubule Severing Enzymes at the Cutting Edge,” Journal of Cell Science, 125, 2561-2569 (2012) web Sharp-JCS-2012.pdf doi: 10.1242/jcs.101139

  3. 3.T.L. Hawkins, M. Mirigian, J. Li, M.S. Yasar, D.L. Sackett, D. Sept, J.L. Ross, “Perturbations in Microtubule Mechanics from Tubulin Preparation,” Cellular and Molecular Bioengineering, 5, 227-238 (2012). web Hawkins-CAMB-2012.pdf

  4. 4.J.L. Ross, “The impacts of molecular motor traffic jams,” Commentary in the Proceedings of the National Academy of Science, USA, 109, 5911-5912 (2012). web Ross-PNAS-2012.pdf doi: 10.1073/pnas.120354210

  5. 5.S. Mukherjee, J.D. Diaz-Valencia, S. Stewman, S. Monnier, U. Rath, A.B. Asenjo, R.A. Charafeddine, H.J. Sosa, J.L. Ross, A. Ma and D.J. Sharp, “Human fidgetin is a microtubule severing enzyme and minus-end depolymerase that regulates mitosis,” Cell Cycle, 11, 1-8 (2012). web Mukerjee-CellCycle-2012.pdf doi: 10.4161/cc.20849

  6. 6.J.L. Ross, book review of “Introduction to Experimental Biophysics: Biological Methods for Physical Scientists,” by Jay Nadeau for Physics Today, 65, 52 (2012). web Ross-PhysicsToday-2012.pdf

  7. 7.L.Conway, D. Wood, E. Tuzel, J.L. Ross, “Motor Transport of Self-Assembled Cargos in Crowded Conditions,” Proceedings of the National Academy of Science, USA, 109, 20814-20819 (2012) web Conway-PNAS-2012.pdf doi: 10.1073/pnas.1209304109

  1. 4.C.P. Samora, B. Mogessie, L. Conway, J.L. Ross, A. Straube, A.D. McAinsh, “MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis,” Nature Cell Biology, 13, 1040-1050 (2011). web Samora-NCB-2011.pdf doi: 10.1038/ncb2297

  2. 5.N. Ma, J. Titus, A. Gable, J.L. Ross, P. Wadsworth, “TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle,” Journal of Cell Biology, 195, 87-98 (2011). web Ma-JCB-2011.pdf doi: 10.1083/jcb.201106149


  1. 1.S. Gon, M. Bendersky, J.L. Ross and M.M. Santore “Manipulating Protein Adsorption using a Patchy Protein-Resistant Brush,” Langmuir, 26, 12147-12154 (2010). web Gon-Langmuir-2010.pdf doi: 10.1021/la1016752

  2. 2.A.G. Hendricks, E. Perlson, J.L. Ross, H.W. Schroeder, M. Tokito, E.L.F. Holzbaur, “Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport,” Current Biology, 20, 697-702 (2010). web Hendricks-CB-2010.pdf doi: 10.1016/j.cub.2010.02.058

  3. 3.J.L. Ross and R. Dixit, “Multiple Color Single Molecule TIRF Imaging and Tracking of MAPs and Motors,” Methods in Cell Biology, Eds. L. Wilson and J.J. Correia, 95, Chapter 26, 521-542 (2010). web  doi: 10.1016/S0091-679X(10)95026-7

  4. 4.R. Dixit and J.L. Ross, “Studying Plus-End Tracking at Single Molecule Resolution Using TIRF,” Methods in Cell Biology, Eds. L. Wilson and J.J. Correia, 95, Chapter 27, 543-554 (2010). web doi: 10.1016/S0091-679X(10)95027-9

  5. 5.T. Hawkins, M. Mirigian, M. Selcuk Yasar, J.L. Ross, “Mechanics of Microtubules,” Journal of Biomechanics, 43, 23-30 (2010) web Hawkins-JBiomech-2010.pdf doi: 10.1016/j.jbiomech.2009.09.005


E. Perlson, G.B. Jeong, J.L. Ross, R. Dixit, K. Wallace, R. Kalb, E.L.F. Holzbaur, “A switch in retrograde signaling from survival to stress in rapid onset neurodegeneration,” Journal of Neuroscience, 29, 9903-9917 (2009). web Perlson-JNeurosci-2009.pdf doi: 10.1523/JNEUROSCI.0813-09.2009


  1. 1.K.J. Rosenberg, J.L. Ross, H.E. Feinstein, S.C. Feinstein, J. Israelachvili, “Complementary dimerization of microtubule-associated protein tau: Implications for microtubule bundling and tau-mediated pathogensis.” Proceedings of the National Academy of Science, USA, 105, 7445-7450 (2008). web Rosenberg-PNAS-2008.pdf doi: 10.1073/pnas.0802036105

  2. 2.J.L. Ross, H. Shuman, E.L.F. Holzbaur, Y.E.Goldman, “Kinesin and dynein-dynactin at intersecting microtubules: Motor density affects dynein function,” Biophysics Journal, 94, 3115-3125 (2008). web  Ross-BPJ-2008.pdf doi: 10.1529/biophysj.107.120014

  3. 3.R. Dixit, J.L. Ross, Y.E.Goldman, E.L.F.Holzbaur, “Differential regulation of dynein and kinesin motor proteins by tau,” Science, 319, 1086-1089 (2008). web Dixit-Science-2008.pdf doi: 10.1126/science.1152993

  4. 4.J.L. Ross, M.Y. Ali, D.M. Warshaw, “Cargo transport: Molecule motors navigate a complex cytoskeleton,” Current Opinion in Cell Biology, 20, 41-47 (2008). web Ross-COCB-2008.pdf doi: 10.1016/


J. Caviston, J.L. Ross, S.M. Antony, M. Tokito, E.L.F. Holzbaur, “A Role for Huntingtin in Dynein/Dynactin-Mediated Vesicle Trafficking,” Proceedings of the National Academy of Sciences, USA, 104, 10045-10050 (2007). web Caviston-PNAS-2007.pdf doi: 10.1073/pnas.0610628104


J.L. Ross, K. Wallace, H. Shuman, Y.E. Goldman, E.L.F. Holzbaur, “Single Dynein-Dynactin Complexes Exhibit Bi-Directional Motion in vitro,” Nature Cell Biology, 8, 562-570 (2006). web Ross-NCB-2006.pdf doi:10.1038/ncb1421


J.L. Ross, C.D. Santangelo, V. Makrides, D.K. Fygenson, “Tau Induces Cooperative Taxol Binding to Microtubules,” Proceedings of the National Academy of Science, USA, 101, 12910-12915 (2004).  web Ross-PNAS-2004.pdf doi: 10.1073/pnas.0402928101


J.L. Ross and D.K. Fygenson, “Mobility of Taxol in Microtubule Bundles,” Biophysical Journal, 84, 3959-3967 (2003).  web  Ross-BPJ-2003.pdf doi: 10.1016/S0006-3495(03)75123-6


  1. 1.D. Zhang, K.D. Grode, S.F. Stewman, J.D. Diaz-Valencia, E. Liebling, U. Rath, T. Riera, J.D. Currie, D.W. Buster, A.B. Asenjo, H.J. Sosa, J.L. Ross, A. Ma, S.L. Rogers and D.J. Sharp “Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration,” Nature Cell Biology, 13, 361-369 (2011). web Zhang-NCB-2011.pdf doi: 10.1038/ncb2206

  2. 2.J.D. Diaz-Valencia, M.M. Morelli, M. Bailey, D. Zhang, D.J. Sharp, and J.L. Ross, “Drosophila Katanin-60 Depolymerizes and Severs at Microtubule Defects,” Biophysical Journal, 100, 2440-2449 (2011). web Diaz-Valencia-BPJ-2011.pdf (Cover Art) doi: 10.1016/j.bpj.2011.03.062

  3. 3.L. Liu, E. Tuzel, J.L. Ross, “Loop formation in microtubules during gliding at high density,” Journal of Physics: Condensed Matter Special Issue: Cooperative Dynamics in Cells, 23, 374104 (2011) web Liu-JoPCM-2011.pdf *Chosen as a top article for 2011! doi: 10.1088/0953-8984/23/37/374104


  1. 1.T.L. Hawkins, D. Sept, B. Moogessie, A. Straube,  J.L. Ross, “Mechanics of Doubly Stabilized Microtubules,” Biophysical Journal, 104, 1517-1528 (2013).  web Hawkins-BPJ-2013.pdf (Cover Art) *Chosen for Biophysical Journal Collection on Molecular Motors and the Cytoskeleton! doi: 10.1016/j.bpj.2013.02.026

  2. 2.J. Pringle, A. Muthukumar, A. Tan, L. Crankshaw, L. Conway, J.L. Ross, “Microtubule Organization by Kinesin Motors and the Microtubule Crosslinking Protein, MAP65,” 25, 374103  Journal of Physics: Condensed Matter, Special issue: Physics of Protein Motility, (2013). web Pringle-JoPCM-2013.pdf doi: 10.1088/0953-8984/25/37/374103

  3. 3.L. Conway, J.L. Ross, “A model system to study transport of self-assembled cargos,” Communicative and Integrative Biology, 6, e-25387 (2013). web Conway-CIB-2013.pdf doi: 10.4161/cib.25387

  4. 4.J.D. Diaz-Valencia, M. Bailey, J.L. Ross, “Purification and Biophysical Analysis of Microtubule-Severing Enzymes In Vitro,” Methods in Cell Biology, Eds. L. Wilson and J.J. Correia, Chapter 13, 191-213 (2013). web

  1. 5.M. Bailey, L. Conway, M.W. Gramlich, T.L. Hawkins, J.L. Ross, “Modern Methods to Interrogate Microtubule Dynamics,” Integrative Biology, 5, 1324-1333 (2013). web Bailey-IBio-2013.pdf Chosen as an iBiology HOT Article! doi: 10.1039/C3IB40124C


  1. 1.M.W. Gramlich, J. Bae, R. Hayward,  J.L. Ross, “Fluorescence imaging of nanoscale domains in polymer blends using stochastic optical reconstruction microscopy (STORM),” Optics Express 22, 8438–8450 (2014). web Gramlich-OpticsExpress-2014.pdf doi:

  2. 2.R. Kemp, A. Chippendale, M. Harrelson, J. Shumway, A. Tan, S. Zuraw, J.L. Ross, “Microscope Project for Undergraduate Laboratories,” accepted at American Journal of Physics (2014).

  3. 3.L. Conway J.L. Ross, “Chapter 11: Measuring Transport of Motor Cargos,” in Fluorescent Methods for Molecular Motors, Christopher Toseland and Natialia Fili Eds. Series: Experientia Supplementum, Vol. 105, Springer (2014).

  4. 4.L. Conway J.L. Ross, “Kinesin Motor Transport is Altered by Macromolecular Crowding and Transiently Associated Microtubule-Associated Proteins,” (2014) ConwayRoss-2014.pdf

  5. 5.L. Conway, M.W. Gramlich, S.M.A. Tabei, J.L. Ross, “Microtubule Orientation and Spacing within Bundles is Critical for Long-Range Kinesin-1 Motility,” Cytoskeleton, 71, 595-610 (2014). web Conway-Cytoskeleton-2014.pdf doi:


  1. 1.K. Stanhope, J.L. Ross, “Microtubules, MAPs, and Motor Proteins,” Methods in Cell Biology, Eds. J.L. Ross, W. Marshall, Chapter 2, 23-37 (2015).

  2. 2.“Building a Cell From Its Component Parts,” Methods in Cell Biology, volume 128, Editors: J.L. Ross and W. Marshall. Published 2015. (Cover Art)

  3. 3.S.K. Blanchard, B.J. Mann, J. Titus, J.L. Ross, P. Wadsworth, “TPX2 inhibits Eg5 by interactions with both motor and microtubule,” Journal of Biological Chemistry (2015). web doi: