Karen Riska, M.S.

Graduate Research Assistant

Telephone: (413) 545-6072
Email: kriska@kin.umass.edu

 

My undergraduate work was completed at the University of Minnesota-Duluth on beautiful Lake Superior. I majored in Biochemistry and Molecular Biology. During my senior year, I  began an independent study and worked with Dr. Ken Wallace in the Department of Biochemistry and Molecular Biology on mitochondrial dysfunction. As a collegiate athlete involved in Cross-Country and Track & Field I took great pleasure in researching the "powerhouse" of the muscle. I continued assisting in the lab after completing my coursework and worked on analyzing possible super-oxide scavengers. During this time I applied for positions in the biochemistry field in the Twin Cities.

While I worked at SurModics, a local biomedical company in the Twin Cities I was asked by my high school coach to assist in coaching cross-country.  For the next two years I juggled work, assistant cross-country coaching and began as an assistant track and field coach in the distance events. As I coached and worked I found my interest in the biomedical field dissipating and my interest in the physiology of the exercising body growing.  I knew that I enjoyed working with people and that I also enjoyed research, so I began to search for masters exercise science programs that would allow me to continue with both of these interests. I completed a Masters of Science in Exercise Science at St. Cloud State University, St. Cloud MN.

Since my arrival at UMASS in the summer of 2004, I have been involved in several laboratory research projects and have completed one of my own. Our laboratory environment is one that allows each of us to work with human subjects to investigate muscle damage, hypertrophy, and atrophy. I have had the opportunity to examine markers of muscle damage using blood and tissue specimens. My own interest is in the molecular pathways involved in muscle atrophy and remodeling as a result of disuse and unloading. In addition, I have participated in collaborative research projects with Hartford Hospital in Connecticut to investigate influence of an acute bout of exercise on skeletal muscle after a high or low dose of statin. This research is important, as Statins are commonly prescribed cholesterol lowering drugs, which have been shown to increase the potential for muscle damage in many individuals. More recently, I have participated in a research project to investigate the influence of a nutritional supplement on muscle strength, soreness and inflammatory markers. I have just recently completed my own research project which investigated the association of a single nucleotide polymorphism in the AKT1 gene on total body composition. I plan to use techniques that I learned while working on these projects for my next research ventures designed to investigate early changes in muscle gene expression with disuse in the AKT1 pathway.

In addition to research, I have served as a TA for the Human Performance and Nutrition course and a TA for the Junior Year Writing couse.

In my free time, I enjoy participating in outdoor activities, particularly running. My favorite time of year to run whenever there is a cool breeze and shade.

 

Awards

  • Doctoral Student Investigator Award-NEACSM Annual Meeting 2004
Grants

  • American College of Sports Medicine Doctoral Student Grant "Effect of AKT1 SNP on Total Body Composition": 4/2005.-$5000.00

Presentations

  • Gene expression profiling of skeletal muscle after spinal cord injury. Presented as a free communication at the NEACSM Annual Meeting, 2004 – Providence, RI (Slide presentation)
  • Gene expression profiling of skeletal muscle after spinal cord injury. Accepted as a poster at the ACSM National Meeting, 2004-Nashville, TN
  • Gene and protein expression after spinal cord injury. Presented as a free communication at the NEACSM Annual Meeting, 2005 – Providence, RI (Slide presentation)
  • AKT1 Association with total body composition. Presented as a poster at SPHHS Poster Day 2006, University of Massachusetts -Amherst
Publications
  •  K.L. Riska, Y-W. Chen, P. Lee, K.F. Lee, M. Urso, M.J. Hubal, P.M. Clarkson. Gene expression profiling of skeletal muscle after spinal cord injury. Medicine and Science in Sport and Exercise. 36(5), 2004