He's Lab

Home | Food Science | UMass

  He's Advanced Analytical Lab
Research    |    People    |    Publications    |    Teaching    |    News    |    Photo Gallery

 Lili He

  Professor and Department Head, Department of Food Science, University of Massachusetts

 Adjunct Faculty, Department of Chemistry, University of Massachusetts 

 Director, Raman, IR, and XRF Core Facility, University of Massachusetts


My research focuses on development and applications of advanced and innovative analytical techniques in solving the critical and emerging issues in environmental, agricultural, and food sciences. The central technique is surface-enhanced Raman spectroscopy (SERS). In addition, surface-enhanced infrared absorption spectroscopy (SEIRAS) and X-ray fluorescent spectroscopy (XRF) are two other techniques of interest. My contribution to the science is the development of various innovative methods that have advanced the analysis of chemical, biological and physical agents in complex systems. These methods have been utilized to fulfill knowledge gaps regarding the prevalence, behavior, and biological fate of the analytes in environmental, agricultural and food systems, and thus to improve the safety and sustainability of our environmental, agricultural and food systems. Check out our recently published SERS review papers:

Lin Z, He L.* Recent advance in SERS techniques for food safety and quality analysis: a brief review. Current Opinion in Food Science. 2019; 28:82-7. doi: https://doi.org/10.1016/j.cofs.2019.10.001.

Guo, Huiyuan, Lili He*, and Baoshan Xing*. "Applications of surface-enhanced Raman spectroscopy in the analysis of nanoparticles in the environment." Environmental Science: Nano 4.11 (2017): 2093-2107. 10.1039/C7EN00653E

Zhang, Ye, Shaojie Zhao, Jinkai Zheng*, and Lili He*. 2017. "Surface-enhanced Raman spectroscopy (SERS) combined techniques for high-performance detection and characterization." TrAC Trends in Analytical Chemistry. http://dx.doi.org/10.1016/j.trac.2017.02.006

Yang, T., Wang, P., Guo, H., He, L.*, 2016. Surface-Enhanced Raman Spectroscopy: A Tool for All Classes of Food Contaminants. Reference Module in Food Sciences. Elsevier, pp. 1–8. doi: http://dx.doi.org/10.1016/B978-0-08-100596-5.21090-1

Pang, Shintaro, Tianxi Yang, and Lili He*. 2016. "Review of surface enhanced raman spectroscopic (SERS) detection of synthetic chemical pesticides."TrAC Trends in Analytical Chemistry.  doi:10.1016/j.trac.2016.06.017

Jinkai Zheng and Lili He*. 2014. Surface-Enhanced Raman Spectroscopy for the Chemical Analysis of Food. Comprehensive Reviews in Food Science and Food Safety. 13 (3), 317-328. http://onlinelibrary.wiley.com/doi/10.1111/1541-4337.12062/abstract

1. Food safety applications, chemical, microbial, and engineered nanomaterial contaminants.

2. Food quality applications, molecular interaction, stability, authenticity

Figure 1. In situ analysis of pesticide penetration.



Figure 2. Evaluation of removal of pesticides from apples using SERS mapping



Figure 3. The sandwich assay for optical and SERS detection of bacteria



Figure 4. Smartphone based optical detection of bacteria.

Figure 5. organic solvent extraction and ultra-sensitive detection of AgNPs using SERS



Figure 6, simutanous determination of type, concentration and size of TiO2 using SERS


Figure 7. AgNP mirror


Funding acknowledgements



 Job opening - postdoc/core facility manager

The postdoc will be the manager of our Raman, IR and XRF core facility and mainly work on the management and providing analytical services to others. This position will likely become permanent in the near future (with career trajectory to core facility director), so I'm looking for candidates who are interested in a long term position at UMass. contact me if inerested. https://explorejobs.uml.edu/amherst/en-us/job/516352?&lApplicationSubSourceID=11250


Office: Chenoweth 344
Tel.: (413) 545-5847

Email: lilihe at umass.edu