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My research focuses on development and applications of the most advanced and innovative analytical techniques in solving the critical and emerging issues in food science. Surface-Enhanced Raman Spectroscopy (SERS) is a combination of Raman spectroscopy and nano-techniques. The use of metallic nanostructure enhances the Raman scattering more than a million times. We have developed various SERS based techniques for food safety and quality. Check out our recently published SERS review papers:

Guo, Huiyuan, Lili He*, and Baoshan Xing*. "Applications of surface-enhanced Raman spectroscopy in the analysis of nanoparticles in the environment." Environmental Science: Nano 4.11 (2017): 2093-2107. 10.1039/C7EN00653E

Zhang, Ye, Shaojie Zhao, Jinkai Zheng*, and Lili He*. 2017. "Surface-enhanced Raman spectroscopy (SERS) combined techniques for high-performance detection and characterization." TrAC Trends in Analytical Chemistry. http://dx.doi.org/10.1016/j.trac.2017.02.006

Yang, T., Wang, P., Guo, H., He, L.*, 2016. Surface-Enhanced Raman Spectroscopy: A Tool for All Classes of Food Contaminants. Reference Module in Food Sciences. Elsevier, pp. 1–8. doi: http://dx.doi.org/10.1016/B978-0-08-100596-5.21090-1

Pang, Shintaro, Tianxi Yang, and Lili He*. 2016. "Review of surface enhanced raman spectroscopic (SERS) detection of synthetic chemical pesticides."TrAC Trends in Analytical Chemistry.  doi:10.1016/j.trac.2016.06.017

Jinkai Zheng and Lili He*. 2014. Surface-Enhanced Raman Spectroscopy for the Chemical Analysis of Food. Comprehensive Reviews in Food Science and Food Safety. 13 (3), 317-328. http://onlinelibrary.wiley.com/doi/10.1111/1541-4337.12062/abstract

1. Food safety applications, chemical, microbial, and engineered nanoparticle contaminants.

2. Food quality applications, molecular interaction, stability, authenticity

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Figure 1. In situ analysis of pesticide penetration.

 

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Figure 2. Evaluation of removal of pesticides from apples using SERS mapping

 

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Figure 3. The sandwich assay for optical and SERS detection of bacteria

 

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Figure 4. Smartphone based optical detection of bacteria.

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Figure 5. ligand based extraction and detection of AgNPs using SERS

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Figure 6, simutanous determination of type, concentration and size of TiO2 using SERS

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Figure 7. AgNP mirror

 

Funding acknowledgements

USDA-NIFA, DHS-NCFPD, NIH-SBIR with Aglitron Inc., PepsiCo Inc., American River Nutrition Inc., Diversified Laboratory, BASF, Inspecto, DSM.

 

 

 

 

 
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Office: Chenoweth 344
Tel.: (413) 545-5847
Email: lilihe at foodsci.umass.edu