LIGO's Eyes-Wide-Open Search for Gravitational Waves Laura Cadonati, Massachusetts Institute of Technology The Laser Interferometer Gravitational-wave Observatory (LIGO) aims to make the first direct observation of gravitational waves, the tiny distorsions of space-time that originate from the universe's most violent events, according to the predictions of General Relativity. Such detection will provide a fundamental new tool for the understanding of our universe. To achieve its goal, LIGO uses three interferometers of km-scale length, two in Hanford, WA, and one in Livingston, LA, measuring differences in length of one part in 10^21 , or 10^-18 m, one thousand times smaller than the nuclear diameter. The detectors have now reached their design sensitivity and the LIGO Scientific Collaboration is actively searching for gravitational wave signatures in the interferometers' data. In this talk I will present one of these ongoing efforts, the "eyes-wide- open" search for unmodeled bursts of gravitational waves. I will describe its challenges and the methods used to optimize the detection efficiency and to suppress the false alarm rate with minimal assumptions on the signal's morphology. I will present the most recent upper limit results and discuss possible future directions for the LIGO burst analysis.