"LIGO and its Quest for Gravitational Waves" Laura Cadonati (MIT) The Laser Interferometer Gravitational-wave Observatory (LIGO) has the ambitious goal of performing the first direct detection of gravitational waves. As predicted by General Relativity, gravitational waves are ripples in the fabric of space-time that can be produced by a wide range of sources, both inside and outside our galaxy, such as black hole collisions, supernova explosions, and rotating pulsars. Their detection will provide a fundamental new tool for the understanding of our universe. To achieve this goal, LIGO uses three Michelson laser interferometers, two in Hanford, WA, and one in Livingston, LA. Each interferometer monitors changes in the relative separation of mirrors at the ends of each of two perpendicular arms of km-scale length, in response to the space-time distortions induced by the passage of gravitational waves. The goal for the initial phase of LIGO is to measure differences in length of one part in 10 21 , or 10 -18 m, one thousand times smaller than the nuclear diameter. The detectors have now reached this design sensitivity and the LIGO Scientific Collaboration is actively searching for gravitational wave signatures in the interferometers' data. This talk will present the physics targeted by LIGO, with an overview of possible gravitational wave sources, data analysis methods, current results and the expected reach of the initial and advanced LIGO configuration.