Laser Interferometers, Gravitational Waves and Echos from the Universe. Laura Cadonati, University of Massachusetts, Amherst On Behalf of the LIGO Scientific Collaboration and the Virgo Collaboration The Laser Interferometer Gravitational-wave Observatory (LIGO) and its sister project Virgo have the ambitious goal of the first direct detection of gravitational waves. Such detection will provide not only a test of General Relativity, but also a fundamental, new probe into the universe. To achieve this goal, LIGO and Virgo use laser interferometers to monitor changes in the relative separation of mirrors at the ends of each of two perpendicular arms of km-scale length, in response to the space-time distortions induced by the passage of gravitational waves. This talk will give an overview of the status and the science of LIGO, with selected results from its initial phase and predictions for the enhanced and advanced detector configurations.