UMass Amherst
 

  Biochem 523: General Biochemistry

Fall 2009
ISB 221
MWF
11:15-12:05


Instructors: Scott C. Garman (garman@biochem.umass.edu) and
  Alejandro P. Heuck (apheuck@biochem.umass.edu)
 

Today is


aGal
Class Day Date Topics

Reading
PC = Pratt & Cornely
PR = Petsko & Ringe

Links Covered
Notes
Lec 1

W

9 Sep

Intro to course

PC 3-21

Course info; PRS setup

Q1, E1

 

Lec 2

F

11 Sep

Overview, organic chem review

PC 24-45; PR 1:0

Lec2 pdf & flash

Q1, E1

 

Lec 3

M

14 Sep

DNA structure

PC 52-62, 75-79; PR 1:2

Lec3 pdf & flash

Q1, E1

 

Lec 4

W

16 Sep

PCR, amino acids

PC 90-103; PR 1:1,3

Lec4 pdf & flash

Q1, E1

 

Lec 5

F

18 Sep

Amino acids, peptides

PC 103-112; PR 1:5,6,7,10

Lec5 pdf & flash

Q1, E1

 

Lec 6

M

21 Sep

Quiz 1, 2° structure

PR 1:4,14,15,16

Q0, Q1 study guide,

Practice Q1 & key,

Q1a key & Q1b key

Lec6 pdf & flash

E1

Add/Drop deadline

Lec 7

W

23 Sep

Conformations, ligand binding

 

Lec7 pdf & flash

E1

 

Lec 8

F

25 Sep

Myoglobin & hemoglobin

PC 116-127

Lec8 pdf & flash, heme movie, Hb movie

E1

 

Lec 9

M

28 Sep

Influenza virus biochemistry

Bouvier_2008, Turner_2009

Lec9 pdf & flash

Q2, E2

 

 

W

30 Sep

Exam 1: 7-9pm Goessmann 20

Make-ups held during class period*

E1 study guide, Practice_E1 & key,

E1 review session flash

 

 

Lec 10

F

2 Oct

Protein purification

Scopes_2000

Lec10 pdf & flash

Q2, E2

 

Lec 11

M

5 Oct

Protein folding

PC 112-116; PR U1:3,4,5

Lec11 pdf & flash

Q2, E2

 

Lec 12

W

7 Oct

Structural biology

PR 5:1,2,3

Lec12 pdf & flash

Q2, E2

 

Lec 13

F

9 Oct

Garman lab research

PR 1:18, U1:5

Lec13 pdf & flash

Q2, E2

 

 

M

12 Oct

Holiday

 

 

 

Columbus Day

Lec 14

T

13 Oct

Reading scientific papers

Lee 2003; Guide to Lee 2003

Lec14 pdf & flash

Q2, E2

 

Lec 15

W

14 Oct

Quiz 2, Bioinformatics

PR 4:6,7,8

Q2 study guide, Practice Q2 & key,

Lec15 pdf & flash

E2

 

Lec 16

F

16 Oct

Bioinformatics, enzyme intro

PC 166-177

Lec16 pdf & flash

E2

 

Lec 17

M

19 Oct

Enzyme mechanism: chymotrypsin

PC 177-192

Lec17 pdf & flash E2

 

Lec 18

W

21 Oct

Enzyme kinetics

PC 198-213; PR U2:1,2,3

Lec18 pdf & flash

E2

 

Lec 19

F

23 Oct

Enzyme kinetics

PC 213-225; PR U2:4

Lec19 pdf & flash

E2

 

Lec 20

M

26 Oct

Review

 

Review2a pdf & flash;

Review2b pdf & flash

E2

Prof Garman finishes

 

W

28 Oct

Exam 2: 7-9pm Goessmann 20

Make-ups held during class period*

E2 study guide, Practice_E2 & key

 

 

Lec 21

F

30 Oct

Intro to Biological membranes

PC 232- 240

Lec21 pdf & pdf with notes

E3 Q3

Prof Heuck starts

Lec 22

M

2 Nov

Membrane proteins

PC 240-247

Lec22 pdf & pdf with notes

E3 Q3

 

Lec 23

W

4 Nov

Membrane transport

PC 248-258

Lec23 pdf & pdf with notes

E3 Q3

 

Lec 24

F

6 Nov

Metabolic reactions

PC 276-298

Lec24 pdf & pdf with notes

E3

 

Lec 25

M

9 Nov

Quiz 3, Glucose Metabolism

PC 302-307

Lec25 pdf with notes

E3

 

 

W

11 Nov

Holiday

 

 

 

Veteran's Day

Lec 26

F

13 Nov

Glucolysis

PC 307-324

Lec 26 pdf & pdf with notes

E3

 

Lec 27

M

16 Nov

Review

TA session 5-7 PM

Study guide. Lec 27 pdf. Practice Exam.

E3

 

 

T

17 Nov

Exam 3: 7-9pm Goessmann 64

Make-ups held during class period*

 

 

 

Lec 28

F

20 Nov

Gluconeogenesis

PC 320-330

Lec 28 pdf & pdf with notes

E4 Q4

Study guide

Lec 29

M

23 Nov

The citric acid cycle
PC 342-364
Lec 29 pdf & pdf with notes

E4 Q4

 

Lec 30

W

25 Nov

Oxidative phosporylation

PC 371-393

 

E4 Q4

 

 

F

27 Nov

Holiday

 

 

 

Thanksgiving

Lec 31

M

30 Nov

Photosynthesis

PC 398-421

 

E4 Q4

 

Lec 32

W

2 Dec

Quiz 4, Fatty acids

PC 424-446

 

E4

 

Lec 33

F

4 Dec

Synthesis of Lipids

PC 446-450

 

E4

 

Lec 34

M

7 Dec

Cholesterol

PC 450-457

E4

 

Lec 35

W

9 Dec

Regulation of Metabolism

PC 500-519

 

E4

 

Lec 36

F

11 Dec

Review

 

 

E4

 

 

M

14 Dec

Exam 4: 4-6pm in Goessmann 64

 

 

 

 

*Make-up exams must be arranged in advance.

 

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