Biochem 523: General Biochemistry |
Fall 2009
ISB 221
|
MWF
11:15-12:05 |
|
 |
| Class |
Day |
Date |
Topics |
Reading
PC
= Pratt & Cornely
PR = Petsko & Ringe
|
Links |
Covered |
Notes |
| Lec 1 |
W |
9 Sep |
Intro to course |
PC 3-21 |
Course info; PRS setup |
Q1, E1 |
|
Lec 2 |
F |
11 Sep |
Overview, organic chem review |
PC 24-45; PR 1:0 |
Lec2 pdf & flash |
Q1, E1 |
|
Lec 3 |
M |
14 Sep |
DNA structure |
PC 52-62, 75-79; PR 1:2 |
Lec3 pdf & flash |
Q1, E1 |
|
Lec 4 |
W |
16 Sep |
PCR, amino acids |
PC 90-103; PR 1:1,3 |
Lec4 pdf & flash |
Q1, E1 |
|
Lec 5 |
F |
18 Sep |
Amino acids, peptides |
PC 103-112; PR 1:5,6,7,10 |
Lec5 pdf & flash |
Q1, E1 |
|
Lec 6 |
M |
21 Sep |
Quiz 1, 2° structure |
PR 1:4,14,15,16 |
Q0, Q1 study guide,
Practice Q1 & key,
Q1a key & Q1b key
Lec6 pdf & flash |
E1 |
Add/Drop deadline |
Lec 7 |
W |
23 Sep |
Conformations, ligand binding |
|
Lec7 pdf & flash |
E1 |
|
Lec 8 |
F |
25 Sep |
Myoglobin & hemoglobin |
PC 116-127 |
Lec8 pdf & flash, heme movie, Hb movie |
E1 |
|
Lec 9 |
M |
28 Sep |
Influenza virus biochemistry |
Bouvier_2008, Turner_2009 |
Lec9 pdf & flash |
Q2, E2 |
|
|
W |
30 Sep |
Exam 1: 7-9pm Goessmann 20 |
Make-ups held during class period* |
E1 study guide, Practice_E1 & key,
E1 review session flash |
|
|
Lec 10 |
F |
2 Oct |
Protein purification |
Scopes_2000 |
Lec10 pdf & flash |
Q2, E2 |
|
Lec 11 |
M |
5 Oct |
Protein folding |
PC 112-116; PR U1:3,4,5 |
Lec11 pdf & flash |
Q2, E2 |
|
Lec 12 |
W |
7 Oct |
Structural biology |
PR 5:1,2,3 |
Lec12 pdf & flash |
Q2, E2 |
|
Lec 13 |
F |
9 Oct |
Garman lab research |
PR 1:18, U1:5 |
Lec13 pdf & flash |
Q2, E2 |
|
|
M |
12 Oct |
Holiday |
|
|
|
Columbus Day |
Lec 14 |
T |
13 Oct |
Reading scientific papers |
Lee 2003; Guide to Lee 2003 |
Lec14 pdf & flash |
Q2, E2 |
|
Lec 15 |
W |
14 Oct |
Quiz 2, Bioinformatics |
PR 4:6,7,8 |
Q2 study guide, Practice Q2 & key,
Lec15 pdf & flash |
E2 |
|
| Lec 16 |
F |
16 Oct |
Bioinformatics, enzyme intro |
PC 166-177 |
Lec16 pdf & flash |
E2 |
|
Lec 17 |
M |
19 Oct |
Enzyme mechanism: chymotrypsin |
PC 177-192 |
Lec17 pdf & flash |
E2 |
|
Lec 18 |
W |
21 Oct |
Enzyme kinetics |
PC 198-213; PR U2:1,2,3 |
Lec18 pdf & flash |
E2 |
|
Lec 19 |
F |
23 Oct |
Enzyme kinetics |
PC 213-225; PR U2:4 |
Lec19 pdf & flash |
E2 |
|
Lec 20 |
M |
26 Oct |
Review |
|
Review2a pdf & flash;
Review2b pdf & flash |
E2 |
Prof Garman finishes |
|
W |
28 Oct |
Exam 2: 7-9pm Goessmann 20 |
Make-ups held during class period* |
E2 study guide, Practice_E2 & key |
|
|
Lec 21 |
F |
30 Oct |
Intro to Biological membranes |
PC 232- 240 |
Lec21 pdf & pdf with notes |
E3 Q3 |
Prof Heuck starts |
Lec 22 |
M |
2 Nov |
Membrane proteins |
PC 240-247 |
Lec22 pdf & pdf with notes |
E3 Q3 |
|
Lec 23 |
W |
4 Nov |
Membrane transport |
PC 248-258 |
Lec23 pdf & pdf with notes |
E3 Q3 |
|
Lec 24 |
F |
6 Nov |
Metabolic reactions |
PC 276-298 |
Lec24 pdf & pdf with notes |
E3 Q3 |
|
Lec 25 |
M |
9 Nov |
Quiz 3, Glucose Metabolism
|
PC 302-324 |
|
E3 |
|
|
W |
11 Nov |
Holiday |
|
|
|
Veteran's Day |
Lec 26 |
F |
13 Nov |
Gluconeogenesis/PPP |
PC 324-335 |
|
E3 |
|
Lec 27 |
M |
16 Nov |
Review |
|
|
E3 |
|
|
T |
17 Nov |
Exam 3: 7-9pm |
Make-ups held during class period* |
|
|
|
Lec 28 |
F |
20 Nov |
The citric acid cycle |
PC 342-364 |
|
E4 Q4 |
|
Lec 29 |
M |
23 Nov |
Oxidative phosporylation |
PC 371-393 |
|
E4 Q4 |
|
Lec 30 |
W |
25 Nov |
Photosynthesis |
PC 398-413 |
|
E4 Q4 |
|
|
F |
27 Nov |
Holiday |
|
|
|
Thanksgiving |
Lec 31 |
M |
30 Nov |
Photosynthesis |
PC 413-421 |
|
E4 Q4 |
|
Lec 32 |
W |
2 Dec |
Quiz 4, Fatty acids |
PC 424-446 |
|
E4 |
|
Lec 33 |
F |
4 Dec |
Synthesis of Lipids |
PC 446-450 |
|
E4 |
|
Lec 34 |
M |
7 Dec |
Cholesterol |
PC 450-457 |
|
E4 |
|
Lec 35 |
W |
9 Dec |
Regulation of Metabolism |
PC 500-519 |
|
E4 |
|
Lec 36 |
F |
11 Dec |
Review |
|
|
E4 |
|
|
M |
14 Dec |
Exam 4: 4-6pm in Goessmann 64 |
|
|
|
|
*Make-up exams must be arranged in advance.
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